Medications and substances for administration by injection (prescription or otherwise) must be procured through legitimate means (i.e. through a pharmacy or the pharmaceutical company). Medications and substances procured by other means may not be the correct substance, may be beyond expiration date, or may have been stored inappropriately, thereby altering composition, safety and efficacy. Pharmaceutical companies may have restrictions on who may procure medications and substances. A nurse should not use another health-care professional purely for the purposes of procurement. Nurses need to follow the manufacturer recommendations for storage and handling as outlined in standards, best practice guidelines and manufacturer recommendations.